2H55: Structure of human Hsp90-alpha bound to the potent water soluble inhibitor PU-DZ8

PDB ID: 2H55Download
MMDB ID: 41606
PDB Deposition Date: 2006/5/25
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 2H55: monomeric; determined by author
Molecular Components in 2H55
Label Count Molecule
Protein (1 molecule)
1
Heat Shock Protein HSP 90-alpha 4
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-FLUORO-8-[(6-IODO-1,3-BENZODIOXOL-5-YL)METHYL]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE2-FLUORO-8-[(6-IODO-1,3-BENZODIOXOL-5-YL)METHYL]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303