2GTK: Structure-based Design of Indole Propionic Acids as Novel PPARag CO-Agonists

PDB ID: 2GTKDownload
MMDB ID: 41574
PDB Deposition Date: 2006/4/28
Updated in MMDB: 2018/10
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 2GTK: dimeric; determined by author and by software (PISA)
Molecular Components in 2GTK
Label Count Molecule
Proteins (2 molecules)
1
Peroxisome Proliferator-activated Receptor Gamma
Molecule annotation
1
Decamer From Nuclear Receptor Coactivator 1
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID(2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303