2G50: The location of the allosteric amino acid binding site of muscle pyruvate kinase

PDB ID: 2G50Download
MMDB ID: 39341
PDB Deposition Date: 2006/2/22
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.65  Å
Source Organism:
Similar Structures:
Biological Unit for 2G50: tetrameric; determined by author and by software (PISA)
Molecular Components in 2G50
Label Count Molecule
Proteins (4 molecules)
4
Pyruvate Kinase Isozymes M1/m2
(Gene symbol: PKM)
Molecule annotation
Chemicals and Non-standard biopolymers (48 molecules)
1
4
MANGANESE (II) IONMANGANESE (II) ION
2
4
POTASSIUM IONPOTASSIUM ION
3
6
SODIUM IONSODIUM ION
4
4
ALANINEALANINE
5
4
PYRUVIC ACIDPYRUVIC ACID
6
13
1,2-ETHANEDIOL1,2-ETHANEDIOL
7
12
GLYCEROLGLYCEROL
8
1
2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303