2G26: Ketopiperazine-Based Renin Inhibitors: Optimization of the "C" Ring

PDB ID: 2G26Download
MMDB ID: 39932
PDB Deposition Date: 2006/2/15
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Molecular Components in 2G26
Label Count Molecule
Proteins (2 molecules)
2
Renin
(Gene symbol: REN)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(5-{[(2R)-1-(4-{3-[(2-METHOXYBENZYL)OXY]PROPOXY}PHENYL)-6-OXOPIPERAZIN-2-YL]METHOXY}-1H-INDOL-1-YL)ACETIC ACID(5-{[(2R)-1-(4-{3-[(2-METHOXYBENZYL)OXY]PROPOXY}PHENYL)-6-OXOPIPERAZIN-2-YL]METHOXY}-1H-INDOL-1-YL)ACETIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303