2G25: E. Coli Pyruvate Dehydrogenase Phosphonolactylthiamin Diphosphate Complex

PDB ID: 2G25Download
MMDB ID: 38776
PDB Deposition Date: 2006/2/15
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 2G25: dimeric; determined by author and by software (PISA)
Molecular Components in 2G25
Label Count Molecule
Proteins (2 molecules)
2
Pyruvate Dehydrogenase E1 Component
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
5
PHOSPHATE IONPHOSPHATE ION
3
2
3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-{(1S)-1-HYDROXY-1-[(R)-HYDROXY(METHOXY)PHOSPHORYL]ETHYL}-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-{(1S)-1-HYDROXY-1-[(R)-HYDROXY(METHOXY)PHOSPHORYL]ETHYL}-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303