2G01: Pyrazoloquinolones as Novel, Selective JNK1 inhibitors

PDB ID: 2G01Download
MMDB ID: 38771
PDB Deposition Date: 2006/2/10
Updated in MMDB: 2006/12
Experimental Method:
x-ray diffraction
Resolution: 3.5  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 2G01: dimeric; determined by author and by software (PISA)
Molecular Components in 2G01
Label Count Molecule
Proteins (2 molecules)
1
Mitogen-activated Protein Kinase 8
Molecule annotation
1
C-jun-amino-terminal Kinase-interacting Protein 1
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
4
SULFATE IONSULFATE ION
2
1
6-CHLORO-9-HYDROXY-1,3-DIMETHYL-1,9-DIHYDRO-4H-PYRAZOLO[3,4-B]QUINOLIN-4-ONE6-CHLORO-9-HYDROXY-1,3-DIMETHYL-1,9-DIHYDRO-4H-PYRAZOLO[3,4-B]QUINOLIN-4-ONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303