2FW3: Crystal Structure Of Rat Carnitine Palmitoyltransferase 2 In Complex With Antidiabetic Drug St1326

Structure (2006) 14 p.628-629
Carnitine palmitoyltransferases (CPTs) are part of the enzymatic system that imports fatty acids into mitochondria. The crystal structure of rat CPT-2 by Rufer et al. (2006) (this issue of Structure) reveals a Y-shaped tunnel for binding the CoA and acyl-carnitine substrates and a hydrophobic insert mediating membrane association.
PDB ID: 2FW3Download
MMDB ID: 43798
PDB Deposition Date: 2006/2/1
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 2FW3: monomeric; determined by author
Molecular Components in 2FW3
Label Count Molecule
Protein (1 molecule)
Carnitine O-palmitoyltransferase II, Mitochondrial(Gene symbol: Cpt2)
Molecule annotation
Chemical (1 molecule)
* Click molecule labels to explore molecular sequence information.

Citing MMDB