2FVJ: A novel anti-adipogenic partial agonist of peroxisome proliferator-activated receptor-gamma (PPARG) recruits pparg-coactivator-1 alpha (PGC1A) but potentiates insulin signaling in vitro

PDB ID: 2FVJDownload
MMDB ID: 39320
PDB Deposition Date: 2006/1/31
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 1.99  Å
Source Organism:
Similar Structures:
Biological Unit for 2FVJ: dimeric; determined by author and by software (PISA)
Molecular Components in 2FVJ
Label Count Molecule
Proteins (2 molecules)
1
Peroxisome Proliferator-activated Receptor Gamma
(Gene symbol: PPARG)
Molecule annotation
1
Nuclear Receptor Coactivator 1
(Gene symbol: NCOA1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
1-(3,4-DIMETHOXYBENZYL)-6,7-DIMETHOXY-4-{[4-(2-METHOXYPHENYL)PIPERIDIN-1-YL]METHYL}ISOQUINOLINE1-(3,4-DIMETHOXYBENZYL)-6,7-DIMETHOXY-4-{[4-(2-METHOXYPHENYL)PIPERIDIN-1-YL]METHYL}ISOQUINOLINE
2
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303