2FTO: Y94F mutant of thymidylate synthase bound to thymidine-5'-phosphate and 10-propargyl-5,8-dideazafolid acid

PDB ID: 2FTODownload
MMDB ID: 38758
PDB Deposition Date: 2006/1/24
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 2FTO: dimeric; determined by author and by software (PISA,PQS)
Molecular Components in 2FTO
Label Count Molecule
Proteins (2 molecules)
2
Thymidylate Synthase
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
PHOSPHATE IONPHOSPHATE ION
2
2
THYMIDINE-5'-PHOSPHATETHYMIDINE-5'-PHOSPHATE
3
2
10-PROPARGYL-5,8-DIDEAZAFOLIC ACID10-PROPARGYL-5,8-DIDEAZAFOLIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303