2FQQ: Crystal structure of human caspase-1 (Cys285->Ala, Cys362->Ala, Cys364->Ala, Cys397->Ala) in complex with 1-methyl-3-trifluoromethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid (2-mercapto-ethyl)-amide

PDB ID: 2FQQDownload
MMDB ID: 39302
PDB Deposition Date: 2006/1/18
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 2FQQ: tetrameric; determined by author and by software (PISA,PQS)
Molecular Components in 2FQQ
Label Count Molecule
Proteins (4 molecules)
2
Caspase-1
(Gene symbol: CASP1)
Molecule annotation
2
Caspase-1
(Gene symbol: CASP1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303