2FJI: Crystal Structure Of The C-terminal Domain Of The Exocyst Subunit Sec6p

The exocyst is a conserved protein complex essential for trafficking secretory vesicles to the plasma membrane. The structure of the C-terminal domain of the exocyst subunit Sec6p reveals multiple helical bundles, which are structurally and topologically similar to Exo70p and the C-terminal domains of Exo84p and Sec15, despite <10% sequence identity. The helical bundles appear to be evolutionarily related molecular scaffolds that have diverged to create functionally distinct exocyst proteins.
PDB ID: 2FJIDownload
MMDB ID: 39279
PDB Deposition Date: 2006/1/2
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 2FJI: monomeric; determined by author
Molecular Components in 2FJI
Label Count Molecule
Protein (1 molecule)
Exocyst Complex Component Sec6(Gene symbol: SEC6)
Molecule annotation
* Click molecule labels to explore molecular sequence information.

Citing MMDB