2FGV: X-ray crystal structure of HIV-1 Protease T80N variant in complex with the inhibitor saquinavir used to explore the role of invariant Thr80 in HIV-1 protease structure, function, and viral infectivity

PDB ID: 2FGVDownload
MMDB ID: 42763
PDB Deposition Date: 2005/12/22
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 2FGV: dimeric; determined by author and by software (PISA)
Molecular Components in 2FGV
Label Count Molecule
Proteins (2 molecules)
2
Protease
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
7
PHOSPHATE IONPHOSPHATE ION
2
1
quinoline-2-carboxylic acidquinoline-2-carboxylic acid
3
1
ASPARAGINEASPARAGINE
4
1
(2S)-2-amino-3-phenylpropane-1,1-diol(2S)-2-amino-3-phenylpropane-1,1-diol
5
1
2-METHYL-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID2-METHYL-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID
6
1
TERTIARY-BUTYLAMINETERTIARY-BUTYLAMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303