2FAK: Crystal structure of Salinosporamide A in complex with the yeast 20S proteasome

PDB ID: 2FAKDownload
MMDB ID: 38719
PDB Deposition Date: 2005/12/7
Updated in MMDB: 2012/10
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 2FAK: 28-meric; determined by author and by software (PISA)
Molecular Components in 2FAK
Label Count Molecule
Proteins (28 molecules)
2
Proteasome Component Y7
(Gene symbol: PRE8)
Molecule annotation
2
Proteasome Component Y13
(Gene symbol: PRE9)
Molecule annotation
2
Proteasome Component Pre6
(Gene symbol: PRE6)
Molecule annotation
2
Proteasome Component Pup2
(Gene symbol: PUP2)
Molecule annotation
2
Proteasome Component Pre5
(Gene symbol: PRE5)
Molecule annotation
2
Proteasome Component C1
(Gene symbol: PRE10)
Molecule annotation
2
Proteasome Component C7-alpha
(Gene symbol: SCL1)
Molecule annotation
2
Proteasome Component Pup1
(Gene symbol: PUP1)
Molecule annotation
2
Proteasome Component Pup3
(Gene symbol: PUP3)
Molecule annotation
2
Proteasome Component C11
(Gene symbol: PRE1)
Molecule annotation
2
Proteasome Component Pre2
(Gene symbol: PRE2)
Molecule annotation
2
Proteasome Component C5
(Gene symbol: PRE7)
Molecule annotation
2
Proteasome Component Pre4
(Gene symbol: PRE4)
Molecule annotation
2
Proteasome Component Pre3
(Gene symbol: PRE3)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
6
(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303