2F9V: HCV NS3 protease domain with NS4a peptide and a ketoamide inhibitor with P1 and P2 cyclopropylalannines

PDB ID: 2F9VDownload
MMDB ID: 43747
PDB Deposition Date: 2005/12/6
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Hepacivirus hominis▼
Similar Structures:
Biological Unit for 2F9V: tetrameric; determined by author and by software (PISA)
Molecular Components in 2F9V
Label Count Molecule
Proteins (4 molecules)
2
NS3 Protease/helicase
Molecule annotation
2
Polyprotein
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
ZINC IONZINC ION
2
1
(2S,8R,9S,15S)-15-CYCLOHEXYL-9,12-BIS(CYCLOPROPYLMETHYL)-8-HYDROXY-20-METHYL-4,7,11,14,17-PENTAOXO-2-PHENYL-18-OXA-3,6,10,12,13,16-HEXAAZAHENICOSAN-1-OIC ACID(2S,8R,9S,15S)-15-CYCLOHEXYL-9,12-BIS(CYCLOPROPYLMETHYL)-8-HYDROXY-20-METHYL-4,7,11,14,17-PENTAOXO-2-PHENYL-18-OXA-3,6,10,12,13,16-HEXAAZAHENICOSAN-1-OIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303