2F54: Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity

PDB ID: 2F54Download
MMDB ID: 38711
PDB Deposition Date: 2005/11/25
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
synthetic construct▼
Similar Structures:
Molecular Components in 2F54
Label Count Molecule
Proteins (10 molecules)
2
HLA Class I Histocompatibility Antigen
Molecule annotation
2
Beta-2-microglobulin
Molecule annotation
2
Cancer/testis Antigen 1B
Molecule annotation
2
T-cell Receptor Alpha Chain
Molecule annotation
2
T-cell Receptor Beta Chain
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303