2F17: Mouse Thiamin Pyrophosphokinase in a Ternary Complex with Pyrithiamin Pyrophosphate and AMP at 2.5 angstrom

PDB ID: 2F17Download
MMDB ID: 36519
PDB Deposition Date: 2005/11/14
Updated in MMDB: 2005/12
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 2F17: dimeric; determined by author and by software (PISA)
Molecular Components in 2F17
Label Count Molecule
Proteins (2 molecules)
2
Thiamin Pyrophosphokinase 1
(Gene symbol: Tpk1)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
6
SULFATE IONSULFATE ION
3
2
1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-2-METHYLPYRIDINIUM1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-2-METHYLPYRIDINIUM
4
1
ADENOSINE MONOPHOSPHATEADENOSINE MONOPHOSPHATE
5
1
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303