2F16: Crystal structure of the yeast 20S proteasome in complex with bortezomib

PDB ID: 2F16Download
MMDB ID: 38209
PDB Deposition Date: 2005/11/14
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 2F16: 28-meric; determined by author and by software (PISA,PQS)
Molecular Components in 2F16
Label Count Molecule
Proteins (28 molecules)
2
Proteasome Component Y7
(Gene symbol: PRE8)
Molecule annotation
2
Proteasome Component Y13
(Gene symbol: PRE9)
Molecule annotation
2
Proteasome Component Pre6
(Gene symbol: PRE6)
Molecule annotation
2
Proteasome Component Pup2
(Gene symbol: PUP2)
Molecule annotation
2
Proteasome Component Pre5
(Gene symbol: PRE5)
Molecule annotation
2
Proteasome Component C1
(Gene symbol: PRE10)
Molecule annotation
2
Proteasome Component C7-alpha
(Gene symbol: SCL1)
Molecule annotation
2
Proteasome Component Pup1
(Gene symbol: PUP1)
Molecule annotation
2
Proteasome Component Pup3
(Gene symbol: PUP3)
Molecule annotation
2
Proteasome Component C11
(Gene symbol: PRE1)
Molecule annotation
2
Proteasome Component Pre2
(Gene symbol: PRE2)
Molecule annotation
2
Proteasome Component C5
(Gene symbol: PRE7)
Molecule annotation
2
Proteasome Component Pre4
(Gene symbol: PRE4)
Molecule annotation
2
Proteasome Component Pre3
(Gene symbol: PRE3)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
6
N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDEN-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303