2EZT: Pyruvate oxidase variant F479W in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate

PDB ID: 2EZTDownload
MMDB ID: 38688
PDB Deposition Date: 2005/11/10
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.29  Å
Source Organism:
Similar Structures:
Biological Unit for 2EZT: tetrameric; determined by author and by software (PISA,PQS)
Molecular Components in 2EZT
Label Count Molecule
Proteins (4 molecules)
4
Pyruvate Oxidase
(Gene symbol: pox5)
Molecule annotation
Chemicals and Non-standard biopolymers (22 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
4
PHOSPHATE IONPHOSPHATE ION
3
2
SODIUM IONSODIUM ION
4
4
2-[(2E)-3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-HYDROXYETHYLIDENE)-4-METHYL-2,3-DIHYDRO-1,3-THIAZOL-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE2-[(2E)-3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-HYDROXYETHYLIDENE)-4-METHYL-2,3-DIHYDRO-1,3-THIAZOL-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE
5
4
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
6
4
PYRUVIC ACIDPYRUVIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303