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2DHF:
CRYSTAL STRUCTURES OF RECOMBINANT HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND 5-DEAZOFOLATE
PDB ID:
2DHF
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MMDB ID:
2643
PDB Deposition Date:
1989/10/25
Updated in MMDB:
2017/12
Experimental Method:
x-ray diffraction
Resolution:
2.3 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2DHF: dimeric; determined by author
Molecular Components in 2DHF
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Dihydrofolate Reductase
(Gene symbol:
DHFR
)
Chemicals and Non-standard biopolymers (2 molecules)
1
2
5-DEAZAFOLIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303