2CL5: Catechol-O-methyltransferase in complex with an inhibitor

PDB ID: 2CL5Download
MMDB ID: 39671
PDB Deposition Date: 2006/4/26
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 2CL5: monomeric; determined by author and by software (PQS)
Molecular Components in 2CL5
Label Count Molecule
Protein (1 molecule)
1
Catechol O-methyltransferase
(Gene symbol: Comt)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
2
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
3
2
(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE
4
3
(R,R)-2,3-BUTANEDIOL(R,R)-2,3-BUTANEDIOL
5
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303