2C6C: membrane-bound glutamate carboxypeptidase II (GCPII) in complex with GPI-18431 (S)-2-(4-iodobenzylphosphonomethyl)-pentanedioic acid

PDB ID: 2C6CDownload
MMDB ID: 38454
PDB Deposition Date: 2005/11/9
Updated in MMDB: 2025/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 2C6C: dimeric; determined by author and by software (PQS)
Molecular Components in 2C6C
Label Count Molecule
Proteins (2 molecules)
2
Glutamate Carboxypeptidase II
(Gene symbol: FOLH1)
Molecule annotation
Chemicals and Non-standard biopolymers (29 molecules)
1
17
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
alpha-D-mannopyranosealpha-D-mannopyranose
3
4
ZINC IONZINC ION
4
2
CALCIUM IONCALCIUM ION
5
2
CHLORIDE IONCHLORIDE ION
6
2
(2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACID(2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303