2C68: Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor

PDB ID: 2C68Download
MMDB ID: 86905
PDB Deposition Date: 2005/11/8
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 2C68: monomeric; determined by author and by software (PQS)
Molecular Components in 2C68
Label Count Molecule
Protein (1 molecule)
1
Cell Division Protein Kinase 2
(Gene symbol: CDK2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(5Z)-5-(3-BROMOCYCLOHEXA-2,5-DIEN-1-YLIDENE)-N-(PYRIDIN-4-YLMETHYL)-1,5-DIHYDROPYRAZOLO[1,5-A]PYRIMIDIN-7-AMINE(5Z)-5-(3-BROMOCYCLOHEXA-2,5-DIEN-1-YLIDENE)-N-(PYRIDIN-4-YLMETHYL)-1,5-DIHYDROPYRAZOLO[1,5-A]PYRIMIDIN-7-AMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303