2C5N: Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design

PDB ID: 2C5NDownload
MMDB ID: 38076
PDB Deposition Date: 2005/10/30
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 2C5N: dimeric; determined by author and by software (PQS)
Molecular Components in 2C5N
Label Count Molecule
Proteins (2 molecules)
1
Cell Division Protein Kinase 2
(Gene symbol: CDK2)
Molecule annotation
1
Cyclin A2
(Gene symbol: CCNA2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINEN-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303