2C3I: CRYSTAL STRUCTURE OF HUMAN PIM1 IN COMPLEX WITH IMIDAZOPYRIDAZIN I

PDB ID: 2C3IDownload
MMDB ID: 36250
PDB Deposition Date: 2005/10/7
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 2C3I: dimeric; determined by author and by software (PISA)
Molecular Components in 2C3I
Label Count Molecule
Proteins (2 molecules)
1
Pimtide
Molecule annotation
1
Proto-oncogene Serine Threonine Protein Kinase Pim1
(Gene symbol: PIM1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-(3-{6-[(CYCLOPROPYLMETHYL)AMINO]IMIDAZO[1,2-B]PYRIDAZIN-3-YL}PHENYL)ETHANONE1-(3-{6-[(CYCLOPROPYLMETHYL)AMINO]IMIDAZO[1,2-B]PYRIDAZIN-3-YL}PHENYL)ETHANONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303