2C1E: Crystal structures of caspase-3 in complex with aza-peptide Michael acceptor inhibitors

PDB ID: 2C1EDownload
MMDB ID: 92255
PDB Deposition Date: 2005/9/14
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.77  Å
Source Organism:
synthetic construct▼
Similar Structures:
Molecular Components in 2C1E
Label Count Molecule
Proteins (3 molecules)
1
Caspase-3 Subunit P17
Molecule annotation
1
Caspase-3 Subunit P12
Molecule annotation
1
Aza-peptide Inhibitor (5s, 8R, 11s)-8-(2-carboxyethyl)-5-(carboxymethyl)-14-(4-ethoxy-4-oxobutanoyl)-11-(1-methylethyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13,14-pentaazahexadecan -16-oic Acid
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303