2BZS: Binding of anti-cancer prodrug CB1954 to the activating enzyme NQO2 revealed by the crystal structure of their complex

PDB ID: 2BZSDownload
MMDB ID: 35394
PDB Deposition Date: 2005/8/22
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 2BZS: dimeric; determined by author and by software (PQS)
Molecular Components in 2BZS
Label Count Molecule
Proteins (2 molecules)
2
NRH Dehydrogenase [quinone] 2
(Gene symbol: NQO2)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
ZINC IONZINC ION
2
2
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
3
2
5-(AZIRIDIN-1-YL)-2,4-DINITROBENZAMIDE5-(AZIRIDIN-1-YL)-2,4-DINITROBENZAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303