2BXU: Design and Discovery of Novel, Potent Thrombin Inhibitors with a Solubilizing Cationic P1-P2-Linker

PDB ID: 2BXUDownload
MMDB ID: 41945
PDB Deposition Date: 2005/7/27
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 2BXU: trimeric; determined by author and by software (PQS)
Molecular Components in 2BXU
Label Count Molecule
Proteins (3 molecules)
1
Alpha Thrombin
Molecule annotation
1
Hirudin
Molecule annotation
1
Alpha Thrombin
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-(2-{[(6-AMINO-2-METHYLPYRIDIN-3-YL)METHYL]AMINO}ETHYL)-6-CHLORO-3-[(2,2-DIFLUORO-2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL1-(2-{[(6-AMINO-2-METHYLPYRIDIN-3-YL)METHYL]AMINO}ETHYL)-6-CHLORO-3-[(2,2-DIFLUORO-2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303