2BVX: Design and Discovery of Novel, Potent Thrombin Inhibitors with a Solubilizing Cationic P1-P2-Linker

PDB ID: 2BVXDownload
MMDB ID: 41943
PDB Deposition Date: 2005/7/4
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 3.2  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 2BVX: trimeric; determined by author and by software (PISA)
Molecular Components in 2BVX
Label Count Molecule
Proteins (3 molecules)
1
Alpha Thrombin
Molecule annotation
1
Hirudin Variant-2
Molecule annotation
1
Alpha Thrombin
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-(5-CHLORO-BENZO[B]THIOPHEN-3-YLMETHYL)-2-[6-CHLORO-OXO-3-(2-PYRIDIN-2-YL-ETHYLAMINO)-2H-PYRAZIN-1-YL]-ACETAMIDEN-(5-CHLORO-BENZO[B]THIOPHEN-3-YLMETHYL)-2-[6-CHLORO-OXO-3-(2-PYRIDIN-2-YL-ETHYLAMINO)-2H-PYRAZIN-1-YL]-ACETAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303