2BVS: Human thrombin complexed with fragment-based small molecules occupying the S1 pocket

PDB ID: 2BVSDownload
MMDB ID: 41941
PDB Deposition Date: 2005/7/4
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 1.4  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 2BVS: trimeric; determined by author and by software (PQS)
Molecular Components in 2BVS
Label Count Molecule
Proteins (3 molecules)
1
Alpha Thrombin
Molecule annotation
1
Hirudin Variant-2
Molecule annotation
1
Alpha Thrombin
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[2-(2-CARBAMOYLMETHOXY-ETHOXY)-ETHYL]-2-[2-(4-CHLORO-PHENYLSULFANYL)-ACETYLAMINO]-3-(4-GUANIDINO-PHENYL)-PROPIONAMIDEN-[2-(2-CARBAMOYLMETHOXY-ETHOXY)-ETHYL]-2-[2-(4-CHLORO-PHENYLSULFANYL)-ACETYLAMINO]-3-(4-GUANIDINO-PHENYL)-PROPIONAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303