2BPS: Ubiquitin-like protein YukD of Bacillus subtilis

The YukD protein in Bacillus subtilis was identified in a hidden Markov model (HMM) search as being related in sequence to ubiquitin. By solving the crystal structure we show that YukD adopts a fold that is most closely related to ubiquitin, yet has the shortest C-terminal tail of all known ubiquitin-like proteins. The endogenous gene of yukD in B. subtilis was disrupted without an obvious phenotypic effect and an inducible copy encoding a C-Myc and His-tagged version of the protein was introduced at the ectopic locus amyE. Conjugation assays performed both in vitro and in vivo indicate that YukD lacks the capacity for covalent bond formation with other proteins.
PDB ID: 2BPSDownload
MMDB ID: 34463
PDB Deposition Date: 2005/4/22
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 2BPS: monomeric; determined by author and by software (PQS)
Molecular Components in 2BPS
Label Count Molecule
Protein (1 molecule)
Yukd Protein(Gene symbol: yukD)
Molecule annotation
* Click molecule labels to explore molecular sequence information.

Citing MMDB