2BEV: Reactivity modulation of human branched-chain alpha-ketoacid dehydrogenase by an internal molecular switch

PDB ID: 2BEVDownload
MMDB ID: 37560
PDB Deposition Date: 2004/11/30
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 2BEV: hexameric; determined by author and by software (PISA)
Molecular Components in 2BEV
Label Count Molecule
Proteins (6 molecules)
2
2-oxoisovalerate Dehydrogenase Alpha Subunit
Molecule annotation
2
2-oxoisovalerate Dehydrogenase Beta Subunit
Molecule annotation
2
Peptide Ala-tyr-arg
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
2
C2-1-HYDROXY-2-METHYL-BUTYL-THIAMIN DIPHOSPHATEC2-1-HYDROXY-2-METHYL-BUTYL-THIAMIN DIPHOSPHATE
2
4
POTASSIUM IONPOTASSIUM ION
3
2
MANGANESE (II) IONMANGANESE (II) ION
4
4
CHLORIDE IONCHLORIDE ION
5
4
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303