2AVO: Kinetics, stability, and structural changes in high resolution crystal structures of HIV-1 protease with drug resistant mutations L24I, I50V, AND G73S

PDB ID: 2AVODownload
MMDB ID: 37090
PDB Deposition Date: 2005/8/30
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 1.1  Å
Source Organism:
Similar Structures:
Biological Unit for 2AVO: dimeric; determined by author and by software (PISA)
Molecular Components in 2AVO
Label Count Molecule
Proteins (2 molecules)
2
POL Polyprotein
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
SULFATE IONSULFATE ION
2
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDEN-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE
4
2
ACETIC ACIDACETIC ACID
5
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303