2ACZ: Complex II (Succinate Dehydrogenase) From E. Coli with Atpenin A5 inhibitor co-crystallized at the ubiquinone binding site

PDB ID: 2ACZDownload
MMDB ID: 36672
PDB Deposition Date: 2005/7/19
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 2ACZ: dodecameric; determined by author and by software (PISA,PQS)
Molecular Components in 2ACZ
Label Count Molecule
Proteins (12 molecules)
3
Succinate Dehydrogenase Flavoprotein Subunit
Molecule annotation
3
Succinate Dehydrogenase Iron-sulfur Protein
(Gene symbol: sdhB)
Molecule annotation
3
Succinate Dehydrogenase Cytochrome B556 Subunit
(Gene symbol: sdhC)
Molecule annotation
3
Succinate Dehydrogenase Hydrophobic Membrane Anchor Protein
Molecule annotation
Chemicals and Non-standard biopolymers (24 molecules)
1
3
OXALOACETATE IONOXALOACETATE ION
2
3
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
3
3
FE2/S2 (INORGANIC) CLUSTERFE2/S2 (INORGANIC) CLUSTER
4
3
IRON/SULFUR CLUSTERIRON/SULFUR CLUSTER
5
3
FE3-S4 CLUSTERFE3-S4 CLUSTER
6
3
HEME B/CHEME B/C
7
3
3-[(2S,4S,5R)-5,6-DICHLORO-2,4-DIMETHYL-1-OXOHEXYL]-4-HYDROXY-5,6-DIMETHOXY-2(1H)-PYRIDINONE3-[(2S,4S,5R)-5,6-DICHLORO-2,4-DIMETHYL-1-OXOHEXYL]-4-HYDROXY-5,6-DIMETHOXY-2(1H)-PYRIDINONE
8
3
CARDIOLIPINCARDIOLIPIN
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303