2A1B: Carboxysome Shell Protein Ccmk2

Bacterial microcompartments are primitive organelles composed entirely of protein subunits. Genomic sequence databases reveal the widespread occurrence of microcompartments across diverse microbes. The prototypical bacterial microcompartment is the carboxysome, a protein shell for sequestering carbon fixation reactions. We report three-dimensional crystal structures of multiple carboxysome shell proteins, revealing a hexameric unit as the basic microcompartment building block and showing how these hexamers assemble to form flat facets of the polyhedral shell. The structures suggest how molecular transport across the shell may be controlled and how structural variations might govern the assembly and architecture of these subcellular compartments.
PDB ID: 2A1BDownload
MMDB ID: 34779
PDB Deposition Date: 2005/6/20
Updated in MMDB: 2012/10
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 2A1B: hexameric; determined by author and by software (PISA)
Molecular Components in 2A1B
Label Count Molecule
Proteins (6 molecules)
Carbon Dioxide Concentrating Mechanism Protein Ccmk Homolog 2
Molecule annotation
* Click molecule labels to explore molecular sequence information.

Citing MMDB