1Z5M: Crystal Structure Of N1-[3-[[5-bromo-2-[[3-[(1-pyrrolidinylcarbonyl)amino]phenyl]amino]-4-pyrimidinyl]amino]propyl]-2,2-dimethylpropanediamide Complexed with Human PDK1

PDB ID: 1Z5MDownload
MMDB ID: 33009
PDB Deposition Date: 2005/3/18
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.17  Å
Source Organism:
Similar Structures:
Biological Unit for 1Z5M: monomeric; determined by author
Molecular Components in 1Z5M
Label Count Molecule
Protein (1 molecule)
1
3-phosphoinositide Dependent Protein Kinase-1
(Gene symbol: PDPK1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
SULFATE IONSULFATE ION
2
1
CHLORIDE IONCHLORIDE ION
3
1
N-(3-{[5-BROMO-2-({3-[(PYRROLIDIN-1-YLCARBONYL)AMINO]PHENYL}AMINO)PYRIMIDIN-4-YL]AMINO}PROPYL)-2,2-DIMETHYLMALONAMIDEN-(3-{[5-BROMO-2-({3-[(PYRROLIDIN-1-YLCARBONYL)AMINO]PHENYL}AMINO)PYRIMIDIN-4-YL]AMINO}PROPYL)-2,2-DIMETHYLMALONAMIDE
4
3
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303