1YY9: Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225

PDB ID: 1YY9Download
MMDB ID: 32982
PDB Deposition Date: 2005/2/24
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 2.605  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 1YY9: trimeric; determined by author
Molecular Components in 1YY9
Label Count Molecule
Proteins (3 molecules)
1
Epidermal Growth Factor Receptor
Molecule annotation
1
Cetuximab FAB Light Chain
Molecule annotation
1
Cetuximab FAB Heavy Chain
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
13
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
beta-D-mannopyranosebeta-D-mannopyranose
3
6
alpha-D-mannopyranosealpha-D-mannopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303