1YHD: The solution structure of YGGX from Escherichia Coli

YggX is a highly conserved protein found only in eubacteria and is proposed to be involved in the bacterial response to oxidative stress. Here we report the solution structure of YggX from Escherichia coli determined by nuclear magnetic resonance spectroscopy. The structure of YggX displays a fold consisting of two N-terminal antiparallel beta-sheets and three alpha-helices, which shares significant structural similarity to the crystal structure of a hypothetical protein PA5148 from Pseudomonas aeruginosa. Previous studies propose YggX as an iron binding protein that is involved in cellular iron trafficking. Our data indicate that the protein alone does not bind iron in vitro, suggesting other cofactors or different conditions may be necessary for metal binding.
PDB ID: 1YHDDownload
MMDB ID: 31558
PDB Deposition Date: 2005/1/7
Updated in MMDB: 2007/11
Experimental Method:
solution nmr
Source Organism:
Similar Structures:
Molecular Components in 1YHD
Label Count Molecule
Protein (1 molecule)
Upf0269 Protein Yggx(Gene symbol: yggX)
Molecule annotation
* Click molecule labels to explore molecular sequence information.

Citing MMDB