1Y8J: Crystal Structure of human NEP complexed with an imidazo[4,5-c]pyridine inhibitor

PDB ID: 1Y8JDownload
MMDB ID: 33711
PDB Deposition Date: 2004/12/13
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 2.25  Å
Source Organism:
Similar Structures:
Biological Unit for 1Y8J: monomeric; determined by author
Molecular Components in 1Y8J
Label Count Molecule
Protein (1 molecule)
1
Neprilysin
(Gene symbol: MME)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
3
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
ZINC IONZINC ION
3
1
ACETATE IONACETATE ION
4
1
2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303