1XH4: Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants

PDB ID: 1XH4Download
MMDB ID: 35036
PDB Deposition Date: 2004/9/17
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.45  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 1XH4: dimeric; determined by author and by software (PISA)
Molecular Components in 1XH4
Label Count Molecule
Proteins (2 molecules)
1
Camp-dependent Protein Kinase, Alpha-catalytic Subunit
Molecule annotation
1
Camp-dependent Protein Kinase Inhibitor, Alpha Form
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[4-({4-[5-(DIMETHYLAMINO)-2-HYDROXYBENZOYL]BENZOYL}AMINO)AZEPAN-3-YL]ISONICOTINAMIDEN-[4-({4-[5-(DIMETHYLAMINO)-2-HYDROXYBENZOYL]BENZOYL}AMINO)AZEPAN-3-YL]ISONICOTINAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303