1WW3: Crystallographic studies on two bioisosteric analogues, N-acetyl-beta-D-glucopyranosylamine and N-trifluoroacetyl-beta-D-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase

PDB ID: 1WW3Download
MMDB ID: 36576
PDB Deposition Date: 2004/12/31
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 1WW3: dimeric; determined by author and by software (PISA,PQS)
Molecular Components in 1WW3
Label Count Molecule
Proteins (2 molecules)
2
Glycogen Phosphorylase, Muscle Form
(Gene symbol: PYGM)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
N-(trifluoroacetyl)-beta-D-glucopyranosylamineN-(trifluoroacetyl)-beta-D-glucopyranosylamine
2
2
PYRIDOXAL-5'-PHOSPHATEPYRIDOXAL-5'-PHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303