1WU1: Factor Xa in complex with the inhibitor 4-[(5-chloroindol-2-yl)sulfonyl]-2-(2-methylpropyl)-1-[[5-(pyridin-4-yl) pyrimidin-2-yl]carbonyl]piperazine

PDB ID: 1WU1Download
MMDB ID: 35866
PDB Deposition Date: 2004/11/29
Updated in MMDB: 2005/12
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 1WU1: dimeric; determined by author
Molecular Components in 1WU1
Label Count Molecule
Proteins (2 molecules)
1
Coagulation Factor X, Heavy Chain
(Gene symbol: F10)
Molecule annotation
1
Coagulation Factor X, Light Chain
(Gene symbol: F10)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
CALCIUM IONCALCIUM ION
2
1
5-CHLORO-2-({3-ISOBUTYL-4-[(5-PYRIDIN-4-YLPYRIMIDIN-2-YL)CARBONYL]PIPERAZIN-1-YL}SULFONYL)-1H-INDOLE5-CHLORO-2-({3-ISOBUTYL-4-[(5-PYRIDIN-4-YLPYRIMIDIN-2-YL)CARBONYL]PIPERAZIN-1-YL}SULFONYL)-1H-INDOLE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303