1WSS: Human Factor Viia-Tissue Factor in Complex with peptide-mimetic inhibitor that has two charged groups in P2 and P4

PDB ID: 1WSSDownload
MMDB ID: 237306
PDB Deposition Date: 2004/11/10
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 1WSS: trimeric; determined by author and by software (PISA)
Molecular Components in 1WSS
Label Count Molecule
Proteins (3 molecules)
1
Coagulation Factor VII
(Gene symbol: F7)
Molecule annotation
1
Coagulation Factor VII
(Gene symbol: F7)
Molecule annotation
1
Tissue Factor
(Gene symbol: F3)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
beta-D-glucopyranosebeta-D-glucopyranose
2
1
alpha-L-fucopyranosealpha-L-fucopyranose
3
9
CALCIUM IONCALCIUM ION
4
1
N-[(3-CARBOXYBENZYL)SULFONYL]ISOLEUCYL-N~1~-{4-[AMINO(IMINO)METHYL]BENZYL}-5-IMINOORNITHINAMIDEN-[(3-CARBOXYBENZYL)SULFONYL]ISOLEUCYL-N~1~-{4-[AMINO(IMINO)METHYL]BENZYL}-5-IMINOORNITHINAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303