1W22: Crystal structure of inhibited human HDAC8

PDB ID: 1W22Download
MMDB ID: 29693
PDB Deposition Date: 2004/6/25
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 1W22: monomeric; determined by author and by software (PISA)
Molecular Components in 1W22
Label Count Molecule
Protein (1 molecule)
1
Histone Deacetylase 8
(Gene symbol: HDAC8)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
ZINC IONZINC ION
2
2
POTASSIUM IONPOTASSIUM ION
3
2
N-HYDROXY-4-(METHYL{[5-(2-PYRIDINYL)-2-THIENYL]SULFONYL}AMINO)BENZAMIDEN-HYDROXY-4-(METHYL{[5-(2-PYRIDINYL)-2-THIENYL]SULFONYL}AMINO)BENZAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303