1V40: First Inhibitor Complex Structure of Human Hematopoietic Prostaglandin D Synthase

PDB ID: 1V40Download
MMDB ID: 30404
PDB Deposition Date: 2003/11/7
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 1V40: dimeric; determined by author and by software (PISA)
Molecular Components in 1V40
Label Count Molecule
Proteins (2 molecules)
2
Glutathione-requiring Prostaglandin D Synthase
(Gene symbol: HPGDS)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
MAGNESIUM IONMAGNESIUM ION
2
2
GLUTATHIONEGLUTATHIONE
3
2
3-(1,3-BENZOTHIAZOL-2-YL)-2-(1,4-DIOXO-1,2,3,4-TETRAHYDROPHTHALAZIN-6-YL)-5-[(E)-2-PHENYLVINYL]-3H-TETRAAZOL-2-IUM3-(1,3-BENZOTHIAZOL-2-YL)-2-(1,4-DIOXO-1,2,3,4-TETRAHYDROPHTHALAZIN-6-YL)-5-[(E)-2-PHENYLVINYL]-3H-TETRAAZOL-2-IUM
4
4
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303