1TYE: Structural basis for allostery in integrins and binding of ligand-mimetic therapeutics to the platelet receptor for fibrinogen

PDB ID: 1TYEDownload
MMDB ID: 29968
PDB Deposition Date: 2004/7/7
Updated in MMDB: 2004/12
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 1TYE: dimeric; determined by author and by software (PISA)
Molecular Components in 1TYE
Label Count Molecule
Proteins (2 molecules)
1
Integrin Alpha-iib
(Gene symbol: ITGA2B)
Molecule annotation
1
Integrin Beta-3
(Gene symbol: ITGB3)
Molecule annotation
Chemicals and Non-standard biopolymers (21 molecules)
1
8
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
alpha-D-mannopyranosealpha-D-mannopyranose
3
2
beta-D-mannopyranosebeta-D-mannopyranose
4
6
CALCIUM IONCALCIUM ION
5
1
CACODYLATE IONCACODYLATE ION
6
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303