1SZC: Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases

PDB ID: 1SZCDownload
MMDB ID: 28287
PDB Deposition Date: 2004/4/5
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.75  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 1SZC: dimeric; determined by author and by software (PISA)
Molecular Components in 1SZC
Label Count Molecule
Proteins (2 molecules)
1
Nad-dependent Deacetylase Hst2
Molecule annotation
1
Histone H4 Peptide
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
ZINC IONZINC ION
2
1
CHLORIDE IONCHLORIDE ION
3
1
CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDECARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE
4
4
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303