1SO2: CATALYTIC DOMAIN OF HUMAN PHOSPHODIESTERASE 3B In COMPLEX WITH A DIHYDROPYRIDAZINE INHIBITOR

PDB ID: 1SO2Download
MMDB ID: 27854
PDB Deposition Date: 2004/3/12
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 1SO2: dimeric; determined by author
Molecular Components in 1SO2
Label Count Molecule
Proteins (2 molecules)
2
Cgmp-inhibited 3',5'-cyclic Phosphodiesterase B
(Gene symbol: PDE3B)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
5
MAGNESIUM IONMAGNESIUM ION
2
4
1-DEOXY-1-[(2-HYDROXYETHYL)(NONANOYL)AMINO]HEXITOL1-DEOXY-1-[(2-HYDROXYETHYL)(NONANOYL)AMINO]HEXITOL
3
2
6-(4-{[2-(3-IODOBENZYL)-3-OXOCYCLOHEX-1-EN-1-YL]AMINO}PHENYL)-5-METHYL-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE6-(4-{[2-(3-IODOBENZYL)-3-OXOCYCLOHEX-1-EN-1-YL]AMINO}PHENYL)-5-METHYL-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303