1SFK: Core (c) Protein From West Nile Virus, Subtype Kunjin

Citation:
Abstract
We have determined the crystal structure of the core (C) protein from the Kunjin subtype of West Nile virus (WNV), closely related to the NY99 strain of WNV, currently a major health threat in the U.S. WNV is a member of the Flaviviridae family of enveloped RNA viruses that contains many important human pathogens. The C protein is associated with the RNA genome and forms the internal core which is surrounded by the envelope in the virion. The C protein structure contains four alpha helices and forms dimers that are organized into tetramers. The tetramers form extended filamentous ribbons resembling the stacked alpha helices seen in HEAT protein structures.
PDB ID: 1SFKDownload
MMDB ID: 28933
PDB Deposition Date: 2004/2/19
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 1SFK: tetrameric; determined by author and by software (PQS)
Molecular Components in 1SFK
Label Count Molecule
Proteins (4 molecules)
4
Core Protein
Molecule annotation
Chemicals (7 molecules)
1
2
2
2
3
1
4
2
* Click molecule labels to explore molecular sequence information.

Citing MMDB
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