1SDT: Crystal structures of HIV protease V82A and L90M mutants reveal changes in indinavir binding site

PDB ID: 1SDTDownload
MMDB ID: 27816
PDB Deposition Date: 2004/2/14
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 1.3  Å
Source Organism:
Similar Structures:
Biological Unit for 1SDT: dimeric; determined by author and by software (PISA)
Molecular Components in 1SDT
Label Count Molecule
Proteins (2 molecules)
2
Protease Retropepsin
(Gene symbol: gag-pol)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
CHLORIDE IONCHLORIDE ION
2
1
N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDEN-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303