1SB1: Novel Non-Covalent Thrombin Inhibitors Incorporating P1 4,5,6,7-Tetrahydrobenzothiazole Arginine Side Chain Mimetics

PDB ID: 1SB1Download
MMDB ID: 27808
PDB Deposition Date: 2004/2/9
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 1SB1: trimeric; determined by author
Molecular Components in 1SB1
Label Count Molecule
Proteins (3 molecules)
1
Prothrombin
Molecule annotation
1
Prothrombin
Molecule annotation
1
Hirugen
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
SODIUM IONSODIUM ION
2
1
N-(BENZYLSULFONYL)-3-CYCLOHEXYLALANYL-N-(2-AMINO-1,3-BENZOTHIAZOL-6-YL)PROLINAMIDEN-(BENZYLSULFONYL)-3-CYCLOHEXYLALANYL-N-(2-AMINO-1,3-BENZOTHIAZOL-6-YL)PROLINAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303